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Invitrogen
Sigma-1 Receptor Recombinant Rabbit Monoclonal Antibody (HL2274)
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FIGURE: 1 / 2
Sigma-1 Receptor Antibody (MA5-50470) in IHC (P)
Immunohistochemical analysis of Sigma-1 Receptor using Sigma-1 Receptor Recombinant Monoclonal Antibody (Product # MA5-50470) in Paraffin embedded mouse stomach tissue at a dilution of 1:100. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-50470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2274
Immunogen
Recombinant fragment of human SIGMAR1.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AAG8; aging-associated gene 8 protein; AL024364; membrane protein; mSigmaR1; mSR-1A; mSR-1B; mSR-1C; mSR-1D; mSR-1E; opioid receptor, sigma 1; OPRS1; RP23 167I12.6; SIG 1R; sigma 1 receptor variant SR-1D; sigma 1-type opioid receptor; Sigma-1 Receptor; sigma1 receptor; sigma1-receptor; SR BP; SR31747 binding protein 1; unnamed protein product
Gene Aliases: ALS16; DSMA2; HMNR2; hSigmaR1; OPRS1; SIG-1R; Sig1R; sigma1R; SR-BP; SR-BP1; SRBP
UniProt ID: (Human) Q99720, (Mouse) O55242
Entrez Gene ID: (Human) 10280, (Mouse) 18391
prostaglandin biosynthetic process
nervous system development
cyclooxygenase pathway
opioid receptor signaling pathway
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
negative regulation of nitric oxide biosynthetic process
protein homotrimerization
response to alcohol
regulation of postsynapse assembly
negative regulation of response to endoplasmic reticulum stress
response to methamphetamine hydrochloride
positive regulation of protein localization to nucleolus
regulation of response to endoplasmic reticulum stress
conditioned place preference
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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