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FIGURE: 1 / 5
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
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Protein Aliases: HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9-a/RanBP1; ran-binding protein 1; RANBP1; RANG; testis secretory sperm-binding protein Li 221n; unnamed protein product
Gene Aliases: HTF9A
UniProt ID: (Human) P43487, (Mouse) P34022
Entrez Gene ID: (Human) 5902, (Mouse) 19385, (Rat) 360739
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