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Invitrogen
CYP2C9 Recombinant Rabbit Monoclonal Antibody (23GB5885)
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FIGURE: 1 / 3
CYP2C9 Antibody (MA5-52938) in ICC/IF
Immunocytochemistry analysis of CYP2C9 in HepG2 cells. Sample was incubated with CYP2C9 monoclonal (Product # MA5-52938) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-52938
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB5885
Immunogen
A synthesized peptide derived from human Cytochrome P450 2C9 (440-490AA).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Amount
33 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytochrome P-450 S-mephenytoin 4-hydroxylase; cytochrome P-450MP; cytochrome P450 PB-1; cytochrome P450, family 2, subfamily C, polypeptide 9; flavoprotein-linked monooxygenase; MGC149605; MGC88320; microsomal monooxygenase; unnamed protein product; xenobiotic monooxygenase
Gene Aliases: CPC9; CYP2C; CYP2C10; CYPIIC9; P450-2C9; P450IIC9
UniProt ID: (Human) P11712
Entrez Gene ID: (Human) 1559
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
arachidonic acid 14,15-epoxygenase activity
arachidonic acid 11,12-epoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
(S)-limonene 6-monooxygenase activity
(S)-limonene 7-monooxygenase activity
heme binding
caffeine oxidase activity
(R)-limonene 6-monooxygenase activity
estrogen 2-hydroxylase activity
arachidonate 8,9-epoxygenase activity
fatty acid omega-1 hydroxylase activity
terpenoid metabolic process
xenobiotic metabolic process
steroid metabolic process
cholesterol metabolic process
estrogen metabolic process
monoterpenoid metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
urea metabolic process
monocarboxylic acid metabolic process
xenobiotic catabolic process
long-chain fatty acid biosynthetic process
icosanoid biosynthetic process
oxidative demethylation
cellular organofluorine metabolic process
omega-hydroxylase P450 pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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