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Invitrogen
CaMKII delta Monoclonal Antibody (K52040_13E3)
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FIGURE: 1 / 2
CaMKII delta Antibody (MA5-55902) in IHC (P)
Immunohistochemistry analysis of CaMKII delta in paraffin-embedded myocardium tissue. Sample was incubated with CaMKII delta monoclonal antibody (Product # MA5-55902) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at ro... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-55902
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K52040_13E3
Immunogen
Recombinant human CAMK2D (immunogen range is 321-400).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.45 mg/mL
Amount
22.5 µg
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
Product Specific Information
Sequence of this protein is as follows: LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE
Target Information
CaMKII delta belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium, calmodulin-dependent protein kinase, type II; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase type II delta chain; CaM kinase II; CaM kinase II delta subunit; CaM-kinase II delta chain; CAM2; CaMK-II delta subunit; CAMK2B; CAMK2G; CAMKB; CAMKG; unnamed protein product
Gene Aliases: CAMKD
UniProt ID: (Human) Q13557
Entrez Gene ID: (Human) 817
protein kinase activity
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
protein binding
calmodulin binding
ATP binding
sodium channel inhibitor activity
titin binding
identical protein binding
protein homodimerization activity
ion channel binding
protein serine kinase activity
regulation of cell growth
regulation of the force of heart contraction
regulation of membrane depolarization
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
regulation of heart contraction
positive regulation of cardiac muscle hypertrophy
regulation of cell communication by electrical coupling
positive regulation of cardiac muscle cell apoptotic process
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
endoplasmic reticulum calcium ion homeostasis
regulation of neuronal synaptic plasticity
relaxation of cardiac muscle
long-term synaptic potentiation
regulation of ryanodine-sensitive calcium-release channel activity
regulation of cellular localization
cellular response to calcium ion
cardiac muscle cell contraction
regulation of heart rate by cardiac conduction
regulation of cardiac muscle cell action potential
regulation of cardiac muscle cell action potential involved in regulation of contraction
regulation of cell communication by electrical coupling involved in cardiac conduction
regulation of relaxation of cardiac muscle
negative regulation of sodium ion transmembrane transport
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
regulation of protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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