Search
Invitrogen
DRD1 Recombinant Rabbit Monoclonal Antibody (HL2927)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-56683
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2927
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human Dopamine Receptor D1. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: D1a receptor; Dopamine 1 receptor; dopamine D1 receptor; DRD1; G-protein coupled receptor; unnamed protein product
Gene Aliases: D1R; DADR; DRD1A
UniProt ID: (Human) P21728
Entrez Gene ID: (Human) 1812
synaptic transmission, dopaminergic
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
dopamine receptor signaling pathway
synapse assembly
learning
memory
mating behavior
locomotory behavior
adult walking behavior
associative learning
visual learning
response to xenobiotic stimulus
transmission of nerve impulse
cerebral cortex GABAergic interneuron migration
positive regulation of cell migration
vasodilation
dopamine metabolic process
positive regulation of potassium ion transport
positive regulation of MAPK cascade
regulation of synaptic plasticity
positive regulation of release of sequestered calcium ion into cytosol
regulation of dopamine uptake involved in synaptic transmission
positive regulation of synaptic transmission, glutamatergic
phospholipase C-activating dopamine receptor signaling pathway
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway
modification of postsynaptic structure
presynaptic modulation of chemical synaptic transmission
negative regulation of behavioral fear response
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support