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Invitrogen
Monkeypox Virus A4L (MPXV/USA/2022/MA001) Recombinant Rabbit Monoclonal Antibody (HL2555)
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FIGURE: 1 / 3
Monkeypox Virus A4L (MPXV/USA/2022/MA001) Antibody (MA5-56795) in ICC/IF
Immunocytochemistry analysis of Monkeypox Virus A4L (MPXV/USA/2022/MA001) using Monkeypox Virus A4L (MPXV/USA/2022/MA001) Recombinant Monoclonal Antibody (Product # MA5-56795) in Mock and transfected 293T cells fixed in ice-cold MeOH for 5 min. Monkeypox Virus A4L (MPXV/USA/2022/MA001) antibody diluted at 1:500. Blue: Fluoroshield with DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-56795
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2555
Immunogen
Full length of Monkeypox virus A4L recombinant protein (MPXV_USA_2022_MA001)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The Monkeypox Virus A4L gene encodes a protein that is considered essential for the replication and virulence of the monkeypox virus, a member of the Orthopoxvirus genus, which also includes the variola virus responsible for smallpox. The A4L protein is a DNA-dependent RNA polymerase subunit, playing a crucial role in the transcription of viral DNA into mRNA, which is necessary for the production of viral proteins and the replication of the virus within the host cell. Monkeypox virus causes a disease in humans that is similar to smallpox but generally less severe, characterized by fever, rash, and lymphadenopathy. Due to its critical function in the viral replication cycle, the A4L protein is a significant target for antiviral drug development and research. Understanding the structure and function of the A4L protein can provide insights into the molecular mechanisms of monkeypox virus replication and pathogenesis, aiding in the development of effective therapeutic strategies and diagnostic tools to combat monkeypox infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A4L
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