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Invitrogen
P2X5 Recombinant Rabbit Monoclonal Antibody (HL2773)
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FIGURE: 1 / 2
P2X5 Antibody (MA5-56821) in WB
Western Blot analysis of P2X5 using P2X5 Recombinant Monoclonal Antibody (Product # MA5-56821). Boiled and unboiled Raji whole cell extracts and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with P2X5 antibody diluted at 1:1,000. A HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-56821
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2773
Immunogen
Synthetic peptide encompassing a sequence within the Intracellular domain of human P2X5. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The P2X5 gene encodes a protein that is a member of the purinergic receptor family, P2X receptors. These receptors are ligand-gated ion channels activated by extracellular ATP. The P2X5 protein is primarily involved in the regulation of skeletal muscle, immune response, and sensory neuron functions. Structurally, P2X5 features two transmembrane domains, a large extracellular loop, and intracellular N- and C-termini. P2X5 is known to form both homomeric and heteromeric channels, contributing to its functional diversity in various tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; MGC47755; P2RX5; purinergic receptor P2X, ligand gated ion channel, 5; unnamed protein product
Gene Aliases: LRH-1; P2X5; P2X5R
UniProt ID: (Human) Q93086
Entrez Gene ID: (Human) 5026
purinergic nucleotide receptor activity
transmembrane signaling receptor activity
extracellular ATP-gated cation channel activity
ion channel activity
voltage-gated ion channel activity
ATP binding
ATP-gated ion channel activity
identical protein binding
ligand-gated monoatomic anion channel activity
ion transport
chloride transport
signal transduction
nervous system development
response to pH
response to zinc ion
positive regulation of calcium ion transport into cytosol
response to ATP
purinergic nucleotide receptor signaling pathway
osteoclast maturation
regulation of skeletal muscle tissue regeneration
positive regulation of calcium-mediated signaling
response to calcium ion
excitatory postsynaptic potential
calcium ion transmembrane transport
cation transmembrane transport
anion transmembrane transport
positive regulation of calcium ion import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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