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Invitrogen
NR2F1 Recombinant Rabbit Monoclonal Antibody (24GB430)
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FIGURE: 1 / 3
NR2F1 Antibody (MA5-57133) in ICC/IF
Immunocytochemical staining of NR2F1 in HeLa cells using NR2F1 Recombinant Monoclonal Antibody (Product # MA5-57133) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; NR2F1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57133
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB430
Immunogen
A synthesized peptide derived from human COUP TF1 (aa 1-53)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.6 mg/mL
Amount
60 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 3; chicken ovalbumin upstream promoter-transcription factor I; COUP transcription factor I; COUP-TF I; COUP-TF1; putative new variant 2; putative new variant 5; putative new variant 6; putative new variant 7; transcription factor COUP 1 (chicken ovalbumin upstream promoter 1, v-erb-a homolog-like 3); unnamed protein product; V-erbA-related protein 3
Gene Aliases: BBOAS; BBSOAS; COUP-TF1; COUP-TFI; COUPTF1; COUPTFA; EAR-3; EAR3; ERBAL3; SVP44; TCFCOUP1; TFCOUP1
UniProt ID: (Human) P10589, (Mouse) Q60632
Entrez Gene ID: (Human) 7025, (Mouse) 13865, (Rat) 81808
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
retinoic acid-responsive element binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
neuron migration
regulation of transcription, DNA-templated
nervous system development
regulation of gene expression
negative regulation of neuron projection development
cerebral cortex regionalization
cell differentiation
intracellular receptor signaling pathway
forebrain development
positive regulation of transcription from RNA polymerase II promoter
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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