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Invitrogen
Aldolase A Recombinant Rabbit Monoclonal Antibody (24GB4710)
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FIGURE: 1 / 2
Aldolase A Antibody (MA5-57329) in WB
Western blot analysis of Aldolase A. Total cell lysates (30 μg) from C2C12, H9c2, HAP-1, HeLa, HepG2, and HT-1080 cell lines were loaded and separated by SDS-PAGE. The blot was incubated with Aldolase A Recombinant Monoclonal Antibody (Product # MA5-57329) at a 1:5,000 dilution and HRP-conjugated goat anti-rabbit secondary antibody at a 1:20,000 dilution respectively.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57329
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB4710
Immunogen
A synthesized peptide derived from human Aldolase (aa 7-20)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALDOA; aldolase A; aldolase A (EC 4.1.2.13); aldolase A (EC 4.1.3.13); aldolase A, fructose-bisphosphate; epididymis secretory sperm binding protein Li 87p; fructose 1,6-diphosphate aldolase A (EC 4.1.2.13); fructose-1,6-bisphosphate triosephosphate-lyase; gluconeogenic enzyme; ALDOA_V1; gluconeogenic enzyme; ALDOA_V2; lung cancer antigen NY-LU-1; muscle-type aldolase; unnamed protein product
Gene Aliases: ALDA; Aldo-1; Aldo1; GSD12; HEL-S-87p; RNALDOG5
UniProt ID: (Human) P04075, (Rat) P05065, (Mouse) P05064
Entrez Gene ID: (Human) 226, (Rat) 24189, (Mouse) 11674
response to hypoxia
fructose metabolic process
glycolytic process
ATP biosynthetic process
striated muscle contraction
binding of sperm to zona pellucida
regulation of cell shape
methylglyoxal biosynthetic process
fructose 1,6-bisphosphate metabolic process
response to lipopolysaccharide
response to nicotine
positive regulation of insulin secretion involved in cellular response to glucose stimulus
response to estrogen
muscle cell cellular homeostasis
protein homotetramerization
canonical glycolysis
hexose metabolic process
positive regulation of cell migration
cellular response to glucose starvation
glycolytic process through fructose-6-phosphate
gluconeogenesis
actin filament organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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