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FIGURE: 1 / 4
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ca 2+ dependent phospholipid scramblase 3; ca(2+)-dependent phospholipid scramblase 3; PL scramblase 3; PLS3; unnamed protein product
Gene Aliases: 2210403O21Rik; 2610037N06Rik; ESTM3; Pls3
UniProt ID: (Human) Q9NRY6, (Mouse) Q9JIZ9, (Rat) Q6QBQ4
Entrez Gene ID: (Human) 57048, (Mouse) 70310, (Rat) 360549
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