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Invitrogen
SARS-CoV-2 Omicron Spike Protein S1/S2 (XBB.1) Chimeric Recombinant Human Monoclonal Antibody (D007)
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Product Details
MA5-60608
Product Specifications
Species Reactivity
Virus
Host/Isotype
Human
/ IgG1, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
D007
Immunogen
Recombinant SARS-CoV-2 Omicron XBB.1 Spike ECD Protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Specifically recognize the SARS-CoV-2 Omicron XBB.1 Spike. No cross-reactivity with SARS-CoV-2 XBB.1.5, XBB, BF.7, BA.4/BA.5/BA.5.2, BA.2.75, BQ.1.1, wild type, Alpha, Beta, Delta.. Has cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1) Spike S1+S2 trimer Protein; No cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1.5) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike RBD Protein; SARS-CoV-2 Omicron (XBB) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB) Spike RBD Protein; SARS-CoV-2 Omicron (BF.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4.6/BF.7) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike RBD Protein; SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein; SARS-CoV-2 Omicron (B.1.1.529) Spike RBD Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; SARS-CoV-2 Delta (B.1.617.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Delta (B.1.617.2) Spike RBD Protein; SARS-CoV-2 Beta (B.1.351) Spike S1+S2 trimer Protein; SARS-CoV-2 Beta (B.1.351, B.1.351.2, B.1.351.3) Spike RBD Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike RBD Protein; SARS-CoV-2 Spike S1+S2 (D614G) trimer Protein; SARS-CoV-2 Spike RBD Protein
Target Information
The SARS-CoV-2 Omicron Spike Protein S1/S2 refers to specific regions of the spike (S) protein of the Omicron variant of the SARS-CoV-2 virus, which is responsible for COVID-19. The spike protein is a key component of the virus's structure and plays a critical role in its ability to infect host cells. It is composed of two main subunits: S1 and S2. The S1/S2 designation refers to the cleavage site between these two subunits. This cleavage is a crucial step for the activation of the spike protein, which is necessary for the virus to enter host cells. The cleavage is typically performed by host cell proteases, such as furin. The Omicron variant of SARS-CoV-2 has numerous mutations in the spike protein, including in the S1 and S2 subunits. These mutations can affect the virus's transmissibility, ability to evade the immune response, and the effectiveness of vaccines and treatments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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