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          • Primary Antibodies ›
          • RAE1 alpha/beta/delta/epsilon Antibodies

          Invitrogen

          RAE1 alpha/beta/delta/epsilon Monoclonal Antibody (199205)

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          Cite RAE1 alpha/beta/delta/epsilon Monoclonal Antibody (199205)

          Additional Information:
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          Product Details

          MA5-61040

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          2.5 µg/10^6 cells
          -

          Inhibition Assays (Inhibition)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Mouse

          Host/Isotype

          Rat / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          199205

          Immunogen

          BaF3 mouse pro-B cell line transfected with Rae-1 beta (Accession # NP_033043) and Mouse myeloma cell line NS0-derived recombinant mouse Rae-1 delta Leu29-Ser227 (Accession # Q9JI58)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.5 mg/mL

          Amount

          500 µg

          Purification

          Protein A/G

          Storage buffer

          PBS with trehalose

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3701652

          Product Specific Information

          Reconstitute at 0.5 mg/mL in sterile PBS.

          Target Information

          RAE1 (RNA Export 1) is a gene that plays a pivotal role in the nuclear export of mRNA in eukaryotic cells. This gene encodes a protein that is integral to the mRNA export machinery, ensuring the proper transport of mRNA from the nucleus to the cytoplasm for translation. The gene has several isoforms, including RAE1 alpha, beta, delta, and epsilon, which may have unique or overlapping functions in different tissues or developmental stages. The proper functioning of RAE1 and its isoforms is crucial for maintaining normal cellular processes and gene expression. Disruptions or mutations in the RAE1 gene can lead to significant defects in mRNA export, potentially causing a range of diseases, including neurodevelopmental disorders and cancers. Ongoing research into RAE1 and its various isoforms is essential for a deeper understanding of mRNA transport mechanisms and their broader implications in cellular health and disease.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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