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Invitrogen
GATA1 Monoclonal Antibody (234732)
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Product Details
MA5-61042
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
234732
Immunogen
E. coli-derived recombinant human GATA-1, Met1-Ser413
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: erythroid DNA-binding protein; erythroid transcription factor 1; GATA-binding factor 1; globin transcription factor 1; HGNC:4170; NF-E1 DNA-binding protein; nuclear factor, erythroid 1; transcription factor GATA1; unnamed protein product
Gene Aliases: CNSHA9; ERYF1; GATA-1; GF-1; GF1; HAEADA; NF-E1; NFE1; XLANP; XLTDA; XLTT
UniProt ID: (Human) P15976
Entrez Gene ID: (Human) 2623
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcription cofactor binding
transcription coactivator binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
chromatin DNA binding
sequence-specific DNA binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
C2H2 zinc finger domain binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of cytosolic calcium ion concentration
male gonad development
anatomical structure morphogenesis
regulation of glycoprotein biosynthetic process
regulation of definitive erythrocyte differentiation
cell differentiation
erythrocyte differentiation
megakaryocyte differentiation
platelet formation
basophil differentiation
eosinophil differentiation
organ regeneration
eosinophil fate commitment
negative regulation of apoptotic process
positive regulation of mast cell degranulation
cell fate commitment
positive regulation of erythrocyte differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
system development
erythrocyte development
Sertoli cell development
platelet aggregation
cellular response to lipopolysaccharide
cellular response to cAMP
cellular response to follicle-stimulating hormone stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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