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Invitrogen
FGF9 Monoclonal Antibody (36923)
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Product Details
MA5-61199
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
36923
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF-9, Met1-Ser208
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
500 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; Glia-activating factor; HBGF-9; Heparin-binding growth factor 9; M-FGF-9; unnamed protein product
Gene Aliases: FGF-9; FGF9; GAF; HBFG-9; HBGF-9; SYNS3
UniProt ID: (Human) P31371
Entrez Gene ID: (Human) 2254
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
osteoblast differentiation
eye development
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
protein import into nucleus
signal transduction
smoothened signaling pathway
cell-cell signaling
cell proliferation
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
male gonad development
mesenchymal cell proliferation
positive regulation of gene expression
Wnt signaling pathway
substantia nigra development
neurogenesis
cell differentiation
negative regulation of Wnt signaling pathway
male sex determination
lung development
embryonic limb morphogenesis
regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
inner ear morphogenesis
positive regulation of MAPK cascade
positive regulation of smoothened signaling pathway
vascular endothelial growth factor receptor signaling pathway
regulation of timing of cell differentiation
embryonic digestive tract development
embryonic skeletal system development
epithelial cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of cell division
Sertoli cell proliferation
cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
canonical Wnt signaling pathway
lung-associated mesenchyme development
stem cell proliferation
positive regulation of canonical Wnt signaling pathway
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
positive regulation of stem cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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