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Reconstitute at 0.5 mg/mL in sterile PBS.
RELMgamma belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family, resistin, RELMalpha, and RELMbeta, are 85-94 amino acid, secreted proteins sharing a conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMgamma is most closely related to RELMalpha, but is distinctly secreted in the bone marrow, spleen, lung, and peripheral blood granulocytes. The physiological role of RELMgamma may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELMgamma have not been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RELMgamma; resistin-like beta; resistin-like molecule gamma
Gene Aliases: retn1g
UniProt ID: (Rat) G3V686
Entrez Gene ID: (Rat) 288135
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