Search
Invitrogen
VEGF/PlGF Heterodimer Monoclonal Antibody (146213)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-61238
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
146213
Immunogen
E. coli-derived recombinant human VEGF/PlGF heterodimer, Ala27-Arg191 (VEGF) & Ala21-Arg149 (PIGF)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
500 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The VEGF/PlGF heterodimer is a complex formed by the vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), both of which are important members of the VEGF family involved in angiogenesis and vasculogenesis. VEGF is primarily known for its role in promoting the growth of blood vessels, while PlGF is involved in pathological angiogenesis and inflammation. The heterodimerization of VEGF and PlGF can enhance their biological activities, contributing to processes such as wound healing, tumor growth, and the development of certain diseases characterized by abnormal blood vessel formation. This heterodimer has been a target of interest in therapeutic research, particularly in the context of cancer and ocular diseases, where inhibiting its activity could potentially reduce pathological angiogenesis and improve clinical outcomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support