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Invitrogen
SIGLEC16 Monoclonal Antibody (706045)
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Product Details
MA5-61722
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
706045
Immunogen
Human Siglec-16 peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
SIGLEC16 (Sialic Acid Binding Ig Like Lectin 16) is a gene that encodes a member of the Siglec family of proteins, which are primarily expressed on the surface of immune cells such as macrophages, dendritic cells, and certain types of lymphocytes. These proteins are involved in the recognition of sialic acid-containing glycan structures on the surface of cells, playing a crucial role in cell-cell interactions and immune regulation. SIGLEC16, in particular, is thought to participate in modulating immune responses and maintaining immune homeostasis. It can influence processes such as inflammation, phagocytosis, and the inhibition of immune cell activation. The expression and function of SIGLEC16 can vary among individuals due to genetic polymorphisms, which may impact susceptibility to infections and autoimmune diseases. Understanding the specific roles and mechanisms of SIGLEC16 in immune regulation is important for developing therapeutic strategies aimed at modulating immune responses in various diseases, including inflammatory and autoimmune conditions. Research into SIGLEC16 also provides insights into the broader functions of the Siglec family and their potential as targets for immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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