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Invitrogen
LEFTY2 Monoclonal Antibody (182515)
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Product Details
MA5-61826
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
182515
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Lefty-A, Phe78-Pro366
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
500 µg
Purification
Protein A/G
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endometrial bleeding-associated factor; Left-right determination factor 2; Left-right determination factor A; MGC46222; Protein lefty-2; Protein lefty-A; TGF-beta-4; Transforming growth factor beta-4; unnamed protein product
Gene Aliases: EBAF; LEFTA; LEFTY2; LEFTYA; PSEC0024; TGFB4
UniProt ID: (Human) O00292
Entrez Gene ID: (Human) 7044
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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