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Invitrogen
LC3A Monoclonal Antibody (877005)
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Product Details
MA5-61963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
877005
Immunogen
E. coli-derived recombinant human LC3A
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; LC3-like protein 1; MAP1 light chain 3-like protein 1; MAP1A/1B light chain 3 A; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; Microtubule-asso; Microtubule-associated protein 1 light chain 3 alpha; microtubule-associated proteins 1A/1B light chain 3; Microtubule-associated proteins 1A/1B light chain 3A; MLP3A; RP11-346K17.1
Gene Aliases: ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3; MAP1LC3A
UniProt ID: (Human) Q9H492
Entrez Gene ID: (Human) 84557
autophagosome assembly
mitophagy
mitophagy
autophagy
cellular response to nitrogen starvation
JNK cascade
cellular response to starvation
response to iron(II) ion
response to lead ion
macroautophagy
response to nutrient levels
cellular response to amino acid starvation
p38MAPK cascade
SMAD protein signal transduction
cellular response to hydrogen peroxide
cellular response to copper ion
cellular response to oxygen-glucose deprivation
autophagosome maturation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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