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Invitrogen
Phospho-MYL2 (Ser19) Recombinant Rabbit Monoclonal Antibody (RM484)
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FIGURE: 1 / 1
Phospho-MYL2 (Ser19) Antibody (MA562160) in WB
Western Blot analysis of mouse heart tissue lysate using Phospho-MYL2 (Ser19) recombinant monoclonal antibody (Product # MA562160) at 1:1,000 dilution. The phospho-specificity of RM484 was verified by peptide blocking using a control non-phosphopeptide or phosphopeptide targeting residue Ser19.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA562160
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
RM484
Immunogen
A phospho-peptide corresponding to human Phospho-Myl2 (Ser19).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Purification
Protein A
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts to Myl2 (Myosin Light Chain 2v) only when phosphorylated at Ser19. There is no cross-reactivity to Myl2 that is not phosphorylated. This antibody reacts to human, mouse or rat Phospho-Myl2 (Ser19).
Target Information
Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac myosin light chain 2; cardiac ventricular myosin light chain 2; DKFZp779C0562; MLC2; MYL2; myosin light chain phosphatase; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; S15D myosin regulatory light chain 2; slow cardiac myosin regulatory light chain 2; T160D myosin regulatory light chain 2; unnamed protein product; ventricular myosin light chain 2
Gene Aliases: CMH10; MFM12; MLC-2; MLC-2s/v; MLC-2v; MLC2
UniProt ID: (Human) P10916
Entrez Gene ID: (Human) 4633
regulation of the force of heart contraction
regulation of striated muscle contraction
heart development
actin filament-based movement
negative regulation of cell growth
muscle cell fate specification
cardiac myofibril assembly
ventricular cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
positive regulation of the force of heart contraction
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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