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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Triclosan, chemically known as 5-chloro-2-(2,4-dichlorophenoxy)phenol, is a broad-spectrum antibacterial agent that has been extensively used in various consumer products for over 30 years. It functions by inhibiting bacterial fatty acid synthesis, primarily targeting the enoyl-acyl carrier protein reductase enzyme, which is crucial for bacterial cell membrane production. Triclosan is lipophilic, allowing it to accumulate in human tissues and the environment, leading to concerns about its potential health risks and environmental impact. Studies have shown that triclosan exposure can lead to bacterial resistance, and its widespread use has resulted in its frequent detection in human biological samples and environmental residues. The molecular structure of triclosan includes a phenolic ring with chlorine substitutions, contributing to its antibacterial properties. Despite its effectiveness, the bioaccumulation and potential adverse effects have prompted regulatory scrutiny and a reevaluation of its safety in consumer products.
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