Despite extensive effort on studying inflammatory processes in the CNS of Parkinson's disease (PD) patients, implications of peripheral monocytes are still poorly understood. Here, we set out to obtain a comprehensive picture of circulating myeloid cells in PD patients. We applied a human primary monocyte culture system and flow cytometry-based ... More
GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain.
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PubMed ID30010619
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PubMed ID30606613
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The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
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PubMed ID32917267
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.
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Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.
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JournalNat Neurosci
PubMed ID31959936
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
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Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2.
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PubMed ID32112058
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice.