A Review of Reagents for Fluorescence Microscopy of Cellular Compartments and Structures, Part I: BacMam Labeling and Reagents for Vesicular Structures.
AuthorsDolman NJ, Kilgore JA, Davidson MW,
Journal
PubMed ID23835803
'Fluorescent labeling of vesicular structures in cultured cells, particularly for live cells, can be challenging for a number of reasons. The first challenge is to identify a reagent that will be specific enough where some structures have a number of potential reagents and others very few options. The emergence of ... More
Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction.
AuthorsHeidt T, Courties G, Dutta P, Sager HB, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, van der Lahn AM, Swirski FK, Weissleder R, Nahrendorf M
Journal
PubMed ID24786973
'Macrophages populate the steady-state myocardium. Previously, all macrophages were thought to arise from monocytes; however, it emerged that, in several organs, tissue-resident macrophages may self-maintain through local proliferation.' ... More
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs.
AuthorsDenny MF, Yalavarthi S, Zhao W, Thacker SG, Anderson M, Sandy AR, McCune WJ, Kaplan MJ,
JournalJ Immunol
PubMed ID20164424
'Neutrophil-specific genes are abundant in PBMC microarrays from lupus patients because of the presence of low-density granulocytes (LDGs) in mononuclear cell fractions. The functionality and pathogenicity of these LDGs have not been characterized. We developed a technique to purify LDGs from lupus PBMCs and assessed their phenotype, function, and potential ... More
Glutathione reductase is essential for host defense against bacterial infection.
AuthorsYan J, Ralston MM, Meng X, Bongiovanni KD, Jones AL, Benndorf R, Nelin LD, Joshua Frazier W, Rogers LK, Smith CV, Liu Y,
JournalFree Radic Biol Med
PubMed ID23623936
Glutathione reductase (Gsr) catalyzes the reduction of glutathione disulfide to glutathione, a major cellular antioxidant. We have recently shown that Gsr is essential for host defense against the gram-negative bacteria Escherichia coli in a mouse model of sepsis. Although we have demonstrated that Gsr is required for sustaining the oxidative ... More
Slit2 Inhibits Breast Cancer Metastasis by Activating M1-Like Phagocytic and Antifibrotic Macrophages.
Authors
JournalCancer Res
PubMed ID34400395
Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis.
AuthorsZumerle S, Calì B, Munari F, Angioni R, Di Virgilio F, Molon B, Viola A
JournalCell Rep
PubMed ID30943393
'Extracellular ATP is a signaling molecule exploited by the immune cells for both autocrine regulation and paracrine communication. By performing live calcium imaging experiments, we show that triggered mouse macrophages are able to propagate calcium signals to resting bystander cells by releasing ATP. ATP-based intercellular communication is mediated by P2X4 ... More
Three Lipid Emulsions Reduce Staphylococcus aureus-Stimulated Phagocytosis in Mouse RAW264.7 Cells.
Authors
JournalMicroorganisms
PubMed ID34946079
Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1.
Authors
JournalDis Model Mech
PubMed ID31744815
Propofol specifically suppresses IL-1β secretion but increases bacterial survival in Staphylococcus aureus-infected RAW264.7 cells.
Authors
JournalMol Cell Biochem
PubMed ID29667111
Nuclear ADP-ribosylation drives IFNγ-dependent STAT1α enhancer formation in macrophages.
Authors
JournalNat Commun
PubMed ID34168143
The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis.
Authors
JournalAm J Respir Crit Care Med
PubMed ID31051082
Complement inhibitor factor H expressed by breast cancer cells differentiates CD14+ human monocytes into immunosuppressive macrophages.
Authors
JournalOncoimmunology
PubMed ID32923173
Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis.