HIV-1 and morphine regulation of autophagy in microglia: Limited interactions in the context of HIV-1 infection and opioid abuse.
AuthorsEl-Hage N, Rodriguez M, Dever SM, Masvekar RR, Gewirtz DA, Shacka JJ,
Journal
PubMed ID25355898
'Microglia are the predominant resident central nervous system (CNS) cell type productively infected by human immunodeficiency virus (HIV) type-1, and play a key role in the progression of HIV-associated dementia (HAD). Moreover, neural dysfunction and progression to HAD are accelerated in opiate drug abusers. In the present study, we examined ... More
Neuroprotective effects of mGluR II and III activators against staurosporine- and doxorubicin-induced cellular injury in SH-SY5Y cells: New evidence for a mechanism involving inhibition of AIF translocation.
AuthorsJantas D, Greda A, Leskiewicz M, Grygier B, Pilc A, Lason W,
Journal
PubMed ID25661514
There are several experimental data sets demonstrating the neuroprotective effects of activation of group II and III metabotropic glutamate receptors (mGluR II/III), however, their effect on neuronal apoptotic processes has yet to be fully recognized. Thus, the comparison of the neuroprotective potency of the mGluR II agonist LY354740, mGluR III ... More
Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury.
Authors
JournalCell Metab
PubMed ID32004476
Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers.
Authors
JournalCell Rep
PubMed ID35108543
Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant.
Authors
JournalNat Commun
PubMed ID30479347
Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates.