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Invitrogen
LPAR3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-12569
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the C-terminal of human EDG7.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Due to low expression of EDG receptors, it is recommended to use Femto Signal Substrate for Western blot. A suggested positive control for this product is RH7777 cells transfected with EDG7.
Target Information
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium-mobilizing lysophosphatidic acid receptor LP-A3; EDG7; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; LPA receptor 3; LPA receptor EDG7; LPA-3; LPA3 Receptor; lysophosphatidic acid receptor Edg-7; rhodopsin family G protein-coupled receptor
Gene Aliases: Edg-7; EDG7; GPCR; HOFNH30; LP-A3; LPA3; RP4-678I3
UniProt ID: (Human) Q9UBY5
Entrez Gene ID: (Human) 23566
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
gene expression
positive regulation of calcium ion transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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