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Invitrogen

ATG7 Polyclonal Antibody

View all (26) ATG7 antibodies

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ATG7 Polyclonal Antibody

Product Details

PA1-18299

Applications
Tested Dilution
Publications

Immunohistochemistry (Frozen) (IHC (F))

1:100
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to the C-terminal residues of human APG7.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2062359

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8 °C. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Target Information

This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: APG7; APG7 autophagy 7-like; AT5G45900; ATAPG7; ATATG7; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog; AUTOPHAGY 7; autophagy 7-like; autophagy related 7 homolog; AUTOPHAGY-RELATED 7; autophagy-related protein 7; DKFZp434N0735; hAGP7; K15I22.10; K15I22_10; PEROXISOME UNUSUAL POSITIONING 4; PEUP4; ubiquitin-activating enzyme E1-like protein; unnamed protein product

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Gene Aliases: APG7-LIKE; APG7L; GSA7; SCAR31

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UniProt ID: (Human) O95352, (Rat) Q641Y5

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Entrez Gene ID: (Human) 10533, (Rat) 312647

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Function(s)
protein binding small protein activating enzyme activity Atg12 activating enzyme activity Atg8 activating enzyme activity protein homodimerization activity
Process(es)
autophagosome assembly mitophagy mitophagy liver development protein lipidation autophagy cellular response to nitrogen starvation mitochondrion organization circadian rhythm adult walking behavior cell proliferation cellular response to starvation response to glucose post-embryonic development positive regulation of catabolic process positive regulation of autophagy negative regulation of cardiac muscle cell apoptotic process macroautophagy cerebellar Purkinje cell layer development pyramidal neuron development central nervous system neuron axonogenesis cerebral cortex development protein catabolic process neuron projection development regulation of protein ubiquitination positive regulation of protein modification process response to nutrient levels positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein modification by small protein conjugation cellular response to stress cellular response to reactive oxygen species piecemeal microautophagy of nucleus positive regulation of insulin secretion involved in cellular response to glucose stimulus negative stranded viral RNA replication response to starvation regulation of circadian rhythm regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of programmed cell death negative regulation of neuron apoptotic process innate immune response positive regulation of protein catabolic process negative regulation of phagocytosis neurological system process defense response to virus cardiac muscle cell development regulation of cell development membrane organization chaperone-mediated autophagy protein lipidation involved in autophagosome assembly negative regulation of programmed necrotic cell death positive regulation of mucus secretion cellular response to morphine cellular response to hyperoxia amino acid homeostasis negative regulation of sphingolipid biosynthetic process cellular sphingolipid homeostasis negative regulation of mitochondrial DNA replication response to alcohol synaptic vesicle cycle dendrite arborization positive regulation of mitophagy response to fluoride regulation of hemopoiesis negative regulation of dendrite extension cellular response to sodium arsenite positive regulation of autophagosome assembly
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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