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Cystatin C Polyclonal Antibody
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FIGURE: 1 / 1
Cystatin C Antibody (PA1-31545) in WB
Western Blot analysis of Cystatin C was performed by loading 35 µg (in RIPA buffer) of mouse testis lysates. Proteins were transferred to a membrane and probed with a Cystatin C Polyclonal Antibody (Product # PA1-31545) at a dilution of 0.01 µg/mL.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-31545
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence GTHSLTKFSCKNA, from the C Terminus.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive control of mouse kidney lysate suggested.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AD8; cystatin-3; Cystatin3; CystatinC; MGC117328; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; RP23-250M11.9; unnamed protein product
Gene Aliases: CysC
UniProt ID: (Mouse) P21460
Entrez Gene ID: (Mouse) 13010
eye development
response to hypoxia
defense response
salivary gland development
embryo implantation
positive regulation of cell proliferation
male gonad development
response to xenobiotic stimulus
response to toxic substance
response to carbohydrate
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
response to nutrient levels
response to estradiol
regulation of tissue remodeling
cellular response to oxidative stress
positive regulation of DNA replication
negative regulation of proteolysis
response to axon injury
Sertoli cell development
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
cellular response to hydrogen peroxide
fibril organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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