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Invitrogen
GPR83 Polyclonal Antibody
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FIGURE: 1 / 3
GPR83 Antibody (PA1-41307) in IHC (P)
Immunohistochemistry analysis of GPR83 in various tissues. Samples were incubated with GPR83 polyclonal antibody (Product # PA1-41307) using a dilution of 20 µg/mL. Frozen brain (neurons & glia, image A); frozen tonsil tissue (lymphocytes, image B); and formalin-fixed paraffin embedded tonsil tissue.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-41307
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Chicken,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 200-250 of human GPR83.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with xenopus based on sequence homology.
Immunogen sequence homology: Gorilla (94%).
Target Information
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor; GIR; G-protein coupled receptor 72; G-protein coupled receptor 83; glucocorticoid induced receptor; glucocorticoid-induced receptor; Hcepto9; Jp05; probable G-protein coupled receptor 83; unnamed protein product
Gene Aliases: GIR; GPR72; RP105; RP39; RP82
UniProt ID: (Dog) Q9TTQ9, (Human) Q9NYM4, (Rat) Q8VHD7, (Mouse) P30731
Entrez Gene ID: (Dog) 403699, (Human) 10888, (Chicken) 428093, (Rat) 140595, (Mouse) 14608
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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