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Invitrogen
Kallikrein 11 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-4312
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide: Y(68) I V H L G Q H N L Q K E E G(82)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-4312 detects the Hippostatin/KLK11 protein in human, mouse, and rat samples.
PA1-4312 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~38 kDa protein representing KLK11 in LNCaP cell lysate.
PA1-4312 immunizing peptide corresponds to amino acid residues 68-82 of the 35 kDa human hippostasin/KLK11protein. There is 86% sequence identity to mouse and rat.
Target Information
Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hippostasin; hK11; kallikrein 11; kallikrein g; kallikrein-11 isoform 4; Kallikrein11; serine protease 20; trypsin-like protease; unnamed protein product
Gene Aliases: 2310015I08Rik; IEKD; Klng; PRSS20; TLSP
UniProt ID: (Human) Q9UBX7, (Mouse) Q9QYN3
Entrez Gene ID: (Human) 11012, (Mouse) 56538, (Rat) 292849
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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