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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Suggested positive control: human lymphoblasts for IHC, human and mouse brain for Western blot.
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson's disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
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Protein Aliases: augmented in rheumatoid arthritis 17; BC 300-268; DKFZp434H2111; FLJ45829; LRR kinase 2; LRRK 2; LRRK-2; unnamed protein product
Gene Aliases: 4921513O20Rik; 9330188B09Rik; AURA17; cI-46; D630001M17Rik; DARDARIN; Gm927; PARK8; RIPK7; ROCO2
UniProt ID: (Human) Q5S007, (Mouse) Q5S006
Entrez Gene ID: (Human) 120892, (Rat) 300160, (Mouse) 66725
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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