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Invitrogen
alpha Galactosidase Polyclonal Antibody
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FIGURE: 1 / 8
alpha Galactosidase Antibody (PA5-110620) in IHC (P)
Immunohistochemistry analysis of alpha Galactosidase in human adrenal gland, colon, liver and testis. Samples were incubated with alpha Galactosidase polyclonal antibody (Product # PA5-110620). Shows similar protein distribution across tissues to independent alpha Galactosidase antibody (Product # PA5-51364) (B).
Product Details
PA5-110620
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human alpha Galactosidase. Recombinant protein control fragment (Product #RP-91935).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FDGCYCDSLE NLADGYKHMS LALNRTGRSI VYSCEWPLYM WPFQKPNYTE IRQYCNHWRN FADIDDSWKS IKSILDWTSF NQERIVDVAG PGGWNDPDML VIGNFGLSWN QQVTQMA
Highest antigen sequence indentity to the following orthologs: Mouse - 76%, Rat - 79%.
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: agalsidase alfa; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; alpha-D-galactoside galactohydrolase 1; alpha-gal A; Alpha-galactosidase A; Galactosylgalactosylglucosylceramidase GLA; Melibiase; unnamed protein product
Gene Aliases: GALA; GLA
UniProt ID: (Human) P06280
Entrez Gene ID: (Human) 2717
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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