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Invitrogen
FHL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-110631
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human FHL1. Recombinant protein control fragment (Product #RP-93666).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RFTAVEDQYY CVDCYKNFVA KKCAGCKNPI TGFGKGSSVV AYEGQSWHDY CFHCKIRRAP PLSNN
Highest antigen sequence indentity to the following orthologs: Rat - 85%, Mouse - 85%.
Target Information
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA535K18.1; FHL1; FHL1B; formerly SLIM1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; heart protein with four and a half LIM domains; KYO-T; LIM protein SLIMMER; MGC111107; RP11-535K18.1; skeletal and cardiac muscle SLIM isoform; skeletal muscle LIM-protein 1; unnamed protein product
Gene Aliases: FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA
UniProt ID: (Human) Q13642
Entrez Gene ID: (Human) 2273
muscle organ development
organ morphogenesis
negative regulation of G2/M transition of mitotic cell cycle
negative regulation of cell growth
regulation of atrial cardiac muscle cell membrane depolarization
positive regulation of potassium ion transmembrane transport
negative regulation of G1/S transition of mitotic cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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