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Invitrogen
GNAI2 Polyclonal Antibody
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Product Details
PA5-110736
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human GNAI2. Recombinant protein control fragment (Product #RP-89901).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EEECRQYRAV VYSNTIQSIM AIVKAMGNLQ IDFADPSRAD DARQLFALSC TAEEQGVLPD DLSGVIRRLW ADHGVQACFG RSREYQLNDS AAYYLNDLER
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 96%.
Target Information
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate cyclase-inhibiting G alpha protein; BR; CD49B; GPIa; GTP-binding regulatory protein Gi alpha-2 chain; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; Guanine nucleotide-binding protein G(i) subunit alpha-2; guanine nucleotide-binding protein G(i), alpha-2 subunit; VLA-2; VLAA2
Gene Aliases: GIP; GNAI2; GNAI2B; H_LUCA15.1; H_LUCA16.1
UniProt ID: (Human) P04899
Entrez Gene ID: (Human) 2771
activation of MAPKK activity
adenosine receptor signaling pathway
protein folding
cell cycle
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
G-protein coupled acetylcholine receptor signaling pathway
gamma-aminobutyric acid signaling pathway
response to nutrient
cell proliferation
positive regulation of cell proliferation
intracellular signal transduction
negative regulation of synaptic transmission
cell division
regulation of calcium ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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