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Invitrogen
SUN3 Polyclonal Antibody
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Product Details
PA5-110745
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human SUN3. Recombinant protein control fragment (Product #RP-89513).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TDVPQKSRQL YAIIAEYGSR LYKYQARLRM PKEQLELLKK ESQNLENNFR QILFLIEQID VLKALLRDMK DGMDNNHNWN THGDPVEDPD HTEEVSNLVN
Highest antigen sequence indentity to the following orthologs: Rat - 69%, Mouse - 72%.
Target Information
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hypothetical protein MGC33329; Sad1 and UNC84 domain containing 1; Sad1/unc-84 domain-containing protein 1; SUN domain-containing protein 3; unnamed protein product
Gene Aliases: SUN3; SUNC1
UniProt ID: (Human) Q8TAQ9
Entrez Gene ID: (Human) 256979
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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