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RUVBL1 Polyclonal Antibody
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FIGURE: 1 / 9
RUVBL1 Antibody (PA5-110857) in IHC (P)
Immunohistochemistry analysis of RUVBL1 in human fallopian tube, kidney, lymph node and testis. Samples were incubated with RUVBL1 polyclonal antibody (Product # PA5-110857). Shows similar protein distribution across tissues to independent RUVBL1 antibody (Product # PA5-82708) (B).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-110857
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human RUVBL1. Recombinant protein control fragment (Product #RP-91879).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GPPGTGKTAL ALAIAQELGS KVPFCPMVGS EVYSTEIKKT EVLMENFRRA IGLRIKETKE VYEGEVTELT PCETENPMGG
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; DNA helicase; epididymis secretory sperm binding protein; INO80 complex subunit H; nuclear matrix protein 238; pontin 52; RuvB (E coli homolog)-like 1; RuvB-like AAA ATPase; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIP60-a; TIP60-associated protein 54-alpha; unnamed protein product
Gene Aliases: ECP-54; ECP54; INO80H; NMP 238; NMP238; PONTIN; Pontin52; RVB1; TIH1; TIP49; TIP49A
UniProt ID: (Human) Q9Y265
Entrez Gene ID: (Human) 8607
box C/D snoRNP assembly
telomere maintenance
regulation of DNA replication
regulation of DNA repair
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
regulation of chromosome organization
regulation of apoptotic process
positive regulation of DNA repair
positive regulation of transcription, DNA-templated
regulation of embryonic development
protein stabilization
regulation of cell cycle
regulation of DNA strand elongation
positive regulation of canonical Wnt signaling pathway
telomerase RNA localization to Cajal body
positive regulation of telomere maintenance in response to DNA damage
positive regulation of double-strand break repair via homologous recombination
regulation of double-strand break repair
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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