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Invitrogen
MDH2 Polyclonal Antibody
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Product Details
PA5-110924
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human MDH2. Recombinant protein control fragment (Product #RP-92744).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MLSALARPAS AALRRSFSTS AQNNAKVAVL GASGGIGQPL SLLLKNSPLV SRLTLYDIAH TPGVAADLSH IETKAAVKGY LGPE
Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 96%.
Target Information
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase, mitochondrial; MDH2; mitochondrial malate dehydrogenase 2, NAD; similar to Mus musculus and Sus scrofa MDH; testicular tissue protein Li 120; unnamed protein product
Gene Aliases: DEE51; EIEE51; M-MDH; MDH; Mdh-2; MDH2; MGC:3559; Mor-1; MOR1
UniProt ID: (Human) P40926, (Rat) P04636, (Mouse) P08249
Entrez Gene ID: (Human) 4191, (Rat) 81829, (Mouse) 17448
RNA binding
catalytic activity
oxidoreductase activity
malate dehydrogenase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L-malate dehydrogenase activity
identical protein binding
malate dehydrogenase (NADP+) activity
protein binding
protein self-association
poly(A) RNA binding
dehydrogenase
gluconeogenesis
tricarboxylic acid cycle
malate metabolic process
aerobic respiration
NAD metabolic process
carboxylic acid metabolic process
malate-aspartate shuttle
oxaloacetate metabolic process
internal protein amino acid acetylation
NADH metabolic process
cellular carbohydrate metabolic process
carbohydrate metabolic process
oxidation-reduction process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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