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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • LMTK2 Antibodies

          Invitrogen

          LMTK2 Polyclonal Antibody

          View all (11) LMTK2 antibodies

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          Cite LMTK2 Polyclonal Antibody

          • Antibody Testing Data (1)
          LMTK2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          LMTK2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          LMTK2 Antibody (PA5-111142) in ICC/IF

          Immunofluorescent analysis of LMTK2 in human cell line U-251 MG using LMTK2 Polyclonal Antibody (Product # PA5-111142). Staining shows localization to nuclear speckles, plasma membrane and microtubule organizing center. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LMTK2 Antibody in Immunocytochemistry (ICC/IF)
          LMTK2 Polyclonal Antibody

          Product Details

          PA5-111142

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein corresonding to Human LMTK2. Recombinant protein control fragment (Product #RP-106019).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.6 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2856552

          Product Specific Information

          Immunogen sequence: MLTGDTLSTS LQSSPEVQVP PTSFETEETP RRVPPDSLPT QGETQPTCLD VIVPEDCLHQ DISPDAVTVP VEILSTDART HSLDNRSQDS PGESEETLRL TESDSVLADD ILASRVSVGS SLPELGQELH NKPFSEDHH

          Highest antigen sequence indentity to the following orthologs: Mouse - 40%, Rat - 36%.

          Target Information

          Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; CDK5/p35-regulated kinase; CPRK; cyclin-dependent kinase 5/p35-regulated kinase; FLJ46659; hBREK; kinase phosphatase inhibitor 2; Kinase/phosphatase/inhibitor 2; KPI-2 protein; Lemur tyrosine kinase 2; LMKT2; protein phosphatase 1, regulatory subunit 100; Serine/threonine-protein kinase KPI-2; Serine/threonine-protein kinase LMTK2

          View more View less

          Gene Aliases: AATYK2; BREK; cprk; hBREK; KIAA1079; KPI-2; KPI2; LMR2; LMTK2; PPP1R100

          View more View less

          UniProt ID: (Human) Q8IWU2

          View more View less

          Entrez Gene ID: (Human) 22853

          View more View less

          Function(s)
          protein serine/threonine kinase activity protein phosphatase inhibitor activity protein binding ATP binding myosin VI binding non-receptor serine/threonine protein kinase
          Process(es)
          receptor recycling protein phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation endocytic recycling transferrin transport negative regulation of catalytic activity early endosome to late endosome transport protein autophosphorylation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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