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Invitrogen
TC10 Polyclonal Antibody
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Product Details
PA5-111209
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human TC10. Recombinant protein control fragment (Product #RP-106080).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FDEAIIAILT PKKHTVKKRI GSRCINCCLI T
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Target Information
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 42; ras homolog gene family, member Q; ras-like protein; Ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; Rho-related GTP-binding protein RhoQ
Gene Aliases: ARHQ; HEL-S-42; RASL7A; RHOQ; TC10; TC10A
UniProt ID: (Human) P17081
Entrez Gene ID: (Human) 23433
endocytosis
actin filament organization
signal transduction
small GTPase mediated signal transduction
insulin receptor signaling pathway
regulation of cell shape
establishment of cell polarity
actin cytoskeleton organization
cortical actin cytoskeleton organization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
positive regulation of glucose import
positive regulation of filopodium assembly
negative regulation of protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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