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Invitrogen
Coronin 1A Polyclonal Antibody
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Product Details
PA5-111327
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Coronin 1A. Recombinant protein control fragment (Product #RP-100865).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RELRVNRGLD TGRRRAAPEA SGTPSSDAVS RLEEEMRKLQ ATVQELQKRL DRLEETVQA
Highest antigen sequence indentity to the following orthologs: Mouse - 80%, Rat - 76%.
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding; Clabp coronin; Clipin-A; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein
Gene Aliases: CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; p57; TACO
UniProt ID: (Human) P31146
Entrez Gene ID: (Human) 11151
immunological synapse formation
phagolysosome assembly
calcium ion transport
phagocytosis
movement of cell or subcellular component
actin filament organization
regulation of cell shape
actin cytoskeleton organization
positive regulation of cell migration
leukocyte chemotaxis
negative regulation of vesicle fusion
cell-substrate adhesion
uropod organization
regulation of actin cytoskeleton organization
nerve growth factor signaling pathway
positive regulation of T cell proliferation
T cell homeostasis
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
homeostasis of number of cells within a tissue
positive chemotaxis
negative regulation of actin nucleation
regulation of release of sequestered calcium ion into cytosol
early endosome to recycling endosome transport
cellular response to interleukin-4
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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