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Invitrogen
SEMA4A Polyclonal Antibody
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Product Details
PA5-111376
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human SEMA4A. Recombinant protein control fragment (Product #RP-104975).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PNLNSWKQDM ERGNPEWACA SGPMSRSLRP QSRPQIIKEV LAVPNSILEL PCPHLSALAS YYWSHGPAAV PEASSTVYNG SLLLIVQDGV GGLYQCWATE NGFSYPVISY WVDSQDQTLA LDPELAGIPR EHVKVPLTRV SGGA
Highest antigen sequence indentity to the following orthologs: Rat - 81%, Mouse - 79%.
Target Information
SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sema B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; Semaphorin-4A; Semaphorin-B; unnamed protein product
Gene Aliases: CORD10; RP35; SEMA4A; SEMAB; SEMB; UNQ783/PRO1317
UniProt ID: (Human) Q9H3S1
Entrez Gene ID: (Human) 64218
angiogenesis
neural crest cell migration
adaptive immune response
T cell differentiation involved in immune response
immune system process
nervous system development
axonogenesis
axon guidance
regulation of cell shape
regulation of endothelial cell migration
negative regulation of angiogenesis
cell differentiation
positive regulation of cell migration
T-helper 1 cell differentiation
negative chemotaxis
semaphorin-plexin signaling pathway
positive regulation of excitatory synapse assembly
positive regulation of inhibitory synapse assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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