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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Heparin Cofactor II Antibodies

          Invitrogen

          Heparin Cofactor II Polyclonal Antibody

          View all (16) Heparin Cofactor II antibodies

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          Cite Heparin Cofactor II Polyclonal Antibody

          • Antibody Testing Data (2)
          Heparin Cofactor II Antibody in Immunocytochemistry (ICC/IF)
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          Heparin Cofactor II Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          Heparin Cofactor II Antibody (PA5-111426) in ICC/IF

          Immunofluorecent analysis of Heparin Cofactor II in human cell line Hep G2 using Heparin Cofactor II Polyclonal Antibody (Product # PA5-111426). Staining shows localization to vesicles. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Heparin Cofactor II Antibody in Immunocytochemistry (ICC/IF)
          Heparin Cofactor II Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Heparin Cofactor II Polyclonal Antibody

          Product Details

          PA5-111426

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein corresonding to Human Heparin Cofactor II. Recombinant protein control fragment (Product #RP-101776).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.10 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2856836

          Product Specific Information

          Immunogen sequence: EAQIADFSDP AFISKTNNHI MKLTKGLIKD ALENIDPATQ MMILNCIYFK GSWVNKFPVE MTHNHNFRLN E

          Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 89%.

          Target Information

          The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: HC-II; Heparin cofactor 2; Heparin cofactor II; HLS2; leuserpin 2; Protease inhibitor leuserpin-2; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; Serpin D1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1

          View more View less

          Gene Aliases: D22S673; HC2; HCF2; HCII; HLS2; LS2; SERPIND1; THPH10

          View more View less

          UniProt ID: (Human) P05546

          View more View less

          Entrez Gene ID: (Human) 3053

          View more View less

          Function(s)
          endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity heparin binding protease inhibitor
          Process(es)
          chemotaxis blood coagulation bioluminescence negative regulation of endopeptidase activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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