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          • Primary Antibodies ›
          • SRPK1 Antibodies

          Invitrogen

          SRPK1 Polyclonal Antibody

          View all (23) SRPK1 antibodies

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          Cite SRPK1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          SRPK1 Antibody in Immunocytochemistry (ICC/IF)
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          SRPK1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          SRPK1 Antibody (PA5-111436) in ICC/IF

          Immunofluorescent analysis of SRPK1 in human cell line U-251 MG using SRPK1 Polyclonal Antibody (Product # PA5-111436). Staining shows localization to nucleoplasm, plasma membrane and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SRPK1 Antibody in Immunocytochemistry (ICC/IF)
          SRPK1 Antibody in Western Blot (WB)
          SRPK1 Polyclonal Antibody

          Product Details

          PA5-111436

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein corresonding to Human SRPK1. Recombinant protein control fragment (Product #RP-105044).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Amount

          5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2856846

          Product Specific Information

          Immunogen sequence: NGDSSTSQET DSCTPITSEV SDTMVCQSSS TVGQSFSEQH ISQLQESIRA EIPCEDEQEQ EHNGPLDNKG

          Highest antigen sequence indentity to the following orthologs: Mouse - 63%, Rat - 60%.

          Target Information

          SRPK1 is a serine/threonine kinase that plays a role in the regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. SRPK1 localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: OTTHUMP00000016277; Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR-protein-specific kinase 1; SRSF protein kinase 1; unnamed protein product

          View more View less

          Gene Aliases: SFRSK1; SRPK1

          View more View less

          UniProt ID: (Human) Q96SB4

          View more View less

          Entrez Gene ID: (Human) 6732

          View more View less

          Function(s)
          nucleotide binding magnesium ion binding RNA binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity transferase activity protein serine kinase activity
          Process(es)
          spliceosomal complex assembly mRNA processing protein phosphorylation chromosome segregation RNA splicing cell differentiation sperm chromatin condensation intracellular signal transduction positive regulation of viral genome replication negative regulation of viral genome replication innate immune response regulation of mRNA splicing, via spliceosome regulation of mRNA processing
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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