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          • Primary Antibodies ›
          • GRB7 Antibodies

          Invitrogen

          GRB7 Polyclonal Antibody

          View all (23) GRB7 antibodies

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          Cite GRB7 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          GRB7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          GRB7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          GRB7 Antibody (PA5-111445) in IHC (P)

          Immunohistochemical analysis of GRB7 in human cerebral cortex using GRB7 Polyclonal Antibody (Product # PA5-111445) shows strong cytoplasmic positivity in neuronal cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          GRB7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GRB7 Polyclonal Antibody

          Product Details

          PA5-111445

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Protein corresonding to Human GRB7. Recombinant protein control fragment (Product #RP-104227).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2856855

          Product Specific Information

          Immunogen sequence: QGHTTGSVKP LSRSDAMELD LSPPHLSSSP EDLCPAPGTP PGTPRPPDTP LPEEVKRSQP LLIPTTGRKL

          Highest antigen sequence indentity to the following orthologs: Rat - 59%, Mouse - 57%.

          Target Information

          The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; Growth factor receptor-bound protein 7; OTTHUMP00000164352; unnamed protein product

          View more View less

          Gene Aliases: GRB7

          View more View less

          UniProt ID: (Human) Q14451

          View more View less

          Entrez Gene ID: (Human) 2886

          View more View less

          Function(s)
          RNA binding protein binding lipid binding protein kinase binding phosphatidylinositol binding identical protein binding
          Process(es)
          signal transduction epidermal growth factor receptor signaling pathway insulin receptor signaling pathway negative regulation of translation positive regulation of cell migration stress granule assembly negative regulation of insulin receptor signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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