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Invitrogen
Fra2 Polyclonal Antibody
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Product Details
PA5-111522
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Fra2. Recombinant protein control fragment (Product #RP-103402).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: WMVQPTVITS MSNPYPRSHP YSPLPGLASV PGHMALPRPG VIKTIGTTVG RRRRDEQLS
Highest antigen sequence indentity to the following orthologs: Rat - 41%, Mouse - 100%.
Target Information
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FOS like 2, AP-1 trancription factor subunit; FOS like antigen 2; Fos-related antigen 2; FOSL2; FRA-2; unnamed protein product
Gene Aliases: ACED; FOSL2; FRA2
UniProt ID: (Human) P15408
Entrez Gene ID: (Human) 2355
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
cell morphogenesis
ossification
osteoblast differentiation
response to hypoxia
NK T cell differentiation
chondrocyte differentiation
inflammatory response to antigenic stimulus
keratinocyte development
growth plate cartilage development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
inflammatory response
cell death
response to xenobiotic stimulus
gene expression
B cell differentiation
T cell differentiation
neutrophil differentiation
macrophage differentiation
bone mineralization
osteoclast differentiation
lung development
response to lipopolysaccharide
collagen metabolic process
collagen biosynthetic process
multicellular organism growth
response to interleukin-13
chondrocyte proliferation
myofibroblast differentiation
regulation of multicellular organism growth
B cell proliferation
glucose homeostasis
innate immune response
fat cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
lung alveolus development
smooth muscle tissue development
tissue remodeling
homeostasis of number of cells
homeostasis of number of cells within a tissue
T cell receptor signaling pathway
cartilage development
response to glucocorticoid
bone development
lung connective tissue development
fat pad development
alveolar secondary septum development
mucus secretion
response to interleukin-7
response to Gram-positive bacterium
insulin metabolic process
fat cell apoptotic process
regulation of myofibroblast differentiation
response to bleomycin
response to leukemia inhibitory factor
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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