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Invitrogen
Myeloperoxidase Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-111526
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Myeloperoxidase. Recombinant protein control fragment (Product #RP-103405).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GAAPAVLGEV DTSLVLSSME EAKQLVDKAY KERRESIKQR LR
Highest antigen sequence indentity to the following orthologs: Rat - 74%, Mouse - 76%.
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
nucleosome disassembly
defense response
response to oxidative stress
response to mechanical stimulus
thiocyanate metabolic process
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
defense response to bacterium
hydrogen peroxide catabolic process
negative regulation of apoptotic process
neutrophil-mediated killing of symbiont cell
neutrophil mediated killing of bacterium
neutrophil mediated killing of fungus
cellular oxidant detoxification
neutrophil extracellular trap formation
positive regulation of cholesterol import
response to gold nanoparticle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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