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Invitrogen
Myeloperoxidase Polyclonal Antibody
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Product Details
PA5-111526
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Myeloperoxidase. Recombinant protein control fragment (Product #RP-103405).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GAAPAVLGEV DTSLVLSSME EAKQLVDKAY KERRESIKQR LR
Highest antigen sequence indentity to the following orthologs: Rat - 74%, Mouse - 76%.
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MPO; Myeloperoxidase; unnamed protein product
Gene Aliases: MPO
UniProt ID: (Human) P05164
Entrez Gene ID: (Human) 4353
response to yeast
hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
defense response to bacterium
hydrogen peroxide catabolic process
negative regulation of apoptotic process
defense response to fungus
response to gold nanoparticle
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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