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Invitrogen
TBPL1 Polyclonal Antibody
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Product Details
PA5-111681
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human TBPL1. Recombinant protein control fragment (Product #RP-107837).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CNMPFEIRLP EFTKNNRPHA SYEPELHPAV CYRIKSLRAT LQIFSTGSIT VTGPNVKAVA TAVEQIYPFV FESRKEI
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 21 kDa TBP-like protein; 21-kDA TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-like 1; TATA box-binding protein-related factor 2; TBP-like 1; TBP-like factor; TBP-like protein; TBP-related factor 2; TBP-related protein
Gene Aliases: MGC:8389; MGC:9620; STUD; TBPL1; TLF; TLP; TLP21; TRF2; TRP
UniProt ID: (Human) P62380
Entrez Gene ID: (Human) 9519
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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