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Invitrogen
CD300a Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-139739
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CD300A. Recombinant protein control fragment (Product #RP-90441).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: SGDHSELSQN PKQASPREEL HYASVVFDSN TNRIAAQRPR EEEPDSDYSV IRK
Highest antigen sequence indentity to the following orthologs: Rat - 41%, Mouse - 31%.
Target Information
The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998 [PubMed 9701027]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD300 antigen-like family member A; CD300a antigen; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35HIRp60; immunoglobulin superfamily member 12; inhibitory receptor protein 60; IRC1a; IRC1b; IRC1c; leukocyte membrane antigen; Mcipr1; NK inhibitory receptor; NKRL
Gene Aliases: CLM-8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35H; CMRF35H9; IGSF12; IRC1; IRC1/IRC2; IRC2; IRp60
UniProt ID: (Human) Q9UGN4
Entrez Gene ID: (Human) 11314
signal transduction
negative regulation of B cell proliferation
negative regulation of mast cell activation involved in immune response
negative regulation of MyD88-dependent toll-like receptor signaling pathway
intracellular signal transduction
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
regulation of innate immune response
negative regulation of fibroblast proliferation
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of eosinophil migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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