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Invitrogen
Galectin 14 Polyclonal Antibody
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Product Details
PA5-139873
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LGALS14. Recombinant protein control fragment (Product #RP-109081).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: QFRLHFGHPA IMNSRVFGIW RYEEKCYYLP FEDGKPF
Highest antigen sequence indentity to the following orthologs: Rat - 32%, Mouse - 32%.
Target Information
Galectin-14 is a member of the galectin family of proteins, which are characterized by their affinity for beta-galactoside sugars and involvement in various biological processes including cell-cell adhesion, immune response modulation, and apoptosis. The gene encoding Galectin-14, LGALS14, is located on chromosome 19q13.2. Galectin-14 is predominantly expressed in eosinophils and has been identified to play a role in allergic response and inflammation. It is known to participate in the modulation of immune responses, particularly asthma and other allergic conditions, by interacting with glycoproteins on cell surfaces. The expression of Galectin-14 is elevated during allergic reactions and this molecule is considered a potential biomarker for eosinophilic activity in such conditions. There is ongoing research into the exact mechanisms of Galectin-14 in immune response modulation, which might provide insights into novel therapeutic approaches for managing allergic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Charcot-Leyden crystal protein 2; CLC2; Gal-14; Galectin-14; lectin, galactoside binding soluble 14; lectin, galactoside-binding, soluble, 14; MGC22235; Placental protein 13-like; placental protein 13-like protein
Gene Aliases: CLC2; LGALS14; PPL13
UniProt ID: (Human) Q8TCE9
Entrez Gene ID: (Human) 56891
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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