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Invitrogen
PRCP Polyclonal Antibody
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Product Details
PA5-139904
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PRCP. Recombinant protein control fragment (Product #RP-109245).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: VKCLNISETA TSSLGTLGWS YQACTEVVMP FCTNGVDDMF EPHSWNLKEL SDDCFQQWGV RPRPSWITTM YGGK
Highest antigen sequence indentity to the following orthologs: Mouse - 73%, Rat - 74%.
Target Information
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Angiotensinase C; Lysosomal carboxypeptidase C; Lysosomal Pro-X carboxypeptidase; PRCP; Proline carboxypeptidase; Prolylcarboxypeptidase; prolylcarboxypeptidase (angiotensinase C)
Gene Aliases: HUMPCP; PCP; PRCP
UniProt ID: (Human) P42785
Entrez Gene ID: (Human) 5547
regulation of thyroid hormone mediated signaling pathway
plasma kallikrein-kinin cascade
negative regulation of systemic arterial blood pressure
proteolysis
blood coagulation, intrinsic pathway
glucose homeostasis
regulation of blood vessel endothelial cell migration
angiogenesis involved in wound healing
energy homeostasis
regulation of reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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