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          • Primary Antibodies ›
          • ECEL1 Antibodies

          Invitrogen

          ECEL1 Polyclonal Antibody

          View all (2) ECEL1 antibodies

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          Cite ECEL1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          ECEL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          ECEL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          ECEL1 Antibody (PA5-140008) in IHC (P)

          Immunohistochemical analysis of ECEL1 in human hypothalamus using ECEL1 Polyclonal Antibody (Product # PA5-140008) shows strong cytoplasmic positivity in neurons. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          ECEL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          ECEL1 Polyclonal Antibody

          Product Details

          PA5-140008

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:2,500-1:5,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ECEL1. Recombinant protein control fragment (Product #RP-108557).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Amount

          30 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2927010

          Product Specific Information

          Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

          Immunogen sequence: LFSLTVSLDD RNSSRYVIRI DQDGLTLPER TLYLAQDEDS EKILAAYRVF MERVLSLLGA DAVEQKAQEI LQVEQQLANI TVSEHDDLR

          Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 90%.

          Target Information

          This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: damage induced neuronal endopeptidase; ECEL1; X converting enzyme

          View more View less

          Gene Aliases: DA5D; DINE; ECEX; XCE

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          UniProt ID: (Human) O95672

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          Entrez Gene ID: (Human) 9427

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          Function(s)
          metalloendopeptidase activity metallopeptidase activity
          Process(es)
          respiratory system process proteolysis neuropeptide signaling pathway protein processing
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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